You can go to this site upload a photo and become Simpsonized. I have to say that I am fairly impressed by how the process works. It works better for some faces than others, but it always manages to be somewhere in the ballpark. There are some non-trivial analysis algorithms going on and I have to say it's one of the neatest things I've seen online in a while.
Of course, I had to Simpsonize all of us, and here we are: